An examination of the structure and function of cells, focusing on the molecules and molecular mechanisms mediating the activities of membranes, cellular compartments, protein and vesicular transport and targeting, cytoskeletal construction and dynamics, the cell cycle, regulation of cell size, cell-cell and cell-matrix adhesion, cellular differentiation and the development of multicellular organisms. The course also focuses on how the knowledge in cellular biology was obtained, on the limits to our understanding, and on current advances.