Our research focuses on Biosensors and Biospectroscopy for minimally invasive composition and energetic status assessment of biological systems. This work involves many disciplines including spectroscopy, chemometrics (bioinformatics), image processing, radio frequency analysis and ultrasound to study biomedical problems that involve cellular respiration and metabolism, such as, muscle/blood/lung oxygenation, fetal health, neurodegenerative disease. Professor Burns’ current research deals with fundamental aspects of bioinformatics, non-invasive near-infrared assessment of health in aging and development of smart polymer nanosensors for measurement of low concentration environmental toxins and oxidative stress metabolites. Techniques developed in our research have an impact on medical, biotechnological and environmental fields.